BALTIMORE (NBC) -- An adult and four children are dead following a two-alarm house fire in northeast Baltimore, Maryland.
The overnight fire also injured three people, including two firefighters.
A call shortly after 2 a.m. reported the fire, Baltimore City Fire Department spokesman Kevin Cartwright said.
According to Cartwright it's believed that those who died are a grandmother and four children.
The ages of the children were not immediately released by officials, but family members said that they were ages 1, 3, 5 and 7.
They said the woman who died was 55.
"A total of ten people were in the home, and five escaped before we arrived," Baltimore City Fire Chief James Clack said.
Firefighters said they heard people screaming for help and encountered heavy flames and smoke emanating from the first floor up through the second floor.
"To explain just how intense this fire was, there was an adult male who jumped from the second floor window to escape the flames," Cartwright said.
That man was treated at the scene and taken to the Johns Hopkins Bayview Burn Center.
A family member identified as Barbara Hopkins said that it was her 52-year-old son who jumped, and that he did so head-first.
He wasn't the only one injured.
Upon receiving reports of children trapped inside, firefighters swiftly began operations inside the structure, and two suffered injuries.
"Firefighters took hose lines inside the house to try to suppress the fire when one of our firefighters fell through the second floor, landing on another below," Cartwright said.